African, American, and European researchers working in a 10-year collaboration have released the largest-ever study of African genetic data — more than 4 million genotypes — providing a library of new information on the continent which is thought to be the source of the oldest settlements of modern humans. "This is the largest study to date of African genetic diversity in the nuclear genome," said lead author Sarah Tishkoff, PhD, a geneticist with joint appointments in the School of Medicine and the School of Arts and Sciences. "This long term collaboration, involving an international team of researchers and years of research expeditions to collect samples from populations living in remote regions of Africa, has resulted in novel insights about levels and patterns of genetic diversity in Africa, a region that has been underrepresented in human genetic studies." A slide show of the team's fieldwork, with audio, is available at www.sas.upenn.edu/home/SASFrontiers/tishkoff.html.
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Apr 30 2009, 05:15 PM
Penn Medicine News