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Frequent Heartburn May Predict Cancers of the Throat and Vocal Cord

Frequent history of heartburn elevated risk for throat and vocal cord cancers. Use of antacids lowered risk. Further studies are needed to confirm the protective effect of antacids. PHILADELPHIA — Frequent heartburn was positively associated with...

Published Thu, May 05 2013 10:00 AM by AACR News

Filed under: Press Releases, Research, Cancer, Media Materials, AACR, cancer prevention, American Association for Cancer Research, prevention, Cancer Epidemiology Biomarkers & Prevention, journal, risk, head and neck cancer, gastric reflux, vocal cord cancer, pharynx cancer, throat cancer, heartburn, Dr. Scott M. Langevin, antacids, larynx cancer
American Association for Cancer Research CEO Recognized With Prestigious Award From Fox Chase Cancer Center

PHILADELPHIA — Margaret Foti, Ph.D., M.D. (h.c.), chief executive officer (CEO) of the American Association for Cancer Research (AACR), was honored with the 2013 Stanley P. Reimann Honor Award for her deep and far-reaching contributions to cancer...

Published Thu, May 05 2013 8:00 AM by AACR News

Filed under: Press Releases, Cancer, Media Materials, AACR, American Association for Cancer Research, award, Chief executive officer, Dr. Margaret Foti, CEO, honor, Fox Chase Cancer Center, Stanley P. Reimann Honor Award
Exercise-related Changes in Estrogen Metabolism May Lower Breast Cancer Risk

Physical activity may reduce breast cancer risk by altering estrogen metabolism. Women who did aerobic exercises had an increased ratio of “good” to “bad” metabolites of estrogen. PHILADELPHIA — Changes in estrogen breakdown...

Published Tue, May 05 2013 12:05 AM by AACR News

Filed under: Press Releases, Research, Breast Cancer, exercise, Media Materials, AACR, cancer prevention, American Association for Cancer Research, women, Cancer Epidemiology Biomarkers & Prevention, journal, breast cancer risk, risk, estrogen, metabolism, Dr. Mindy S. Kurzer
Sleep Problems May Increase Risk for Prostate Cancer

Problems falling asleep and staying asleep increased risk for prostate cancer. The association was stronger for advanced disease. Larger studies with longer follow-up are necessary for confirmation. PHILADELPHIA — Men who reported sleep problems...

Published Tue, May 05 2013 12:05 AM by AACR News

Filed under: Press Releases, Research, Cancer, Media Materials, AACR, American Association for Cancer Research, prostate cancer, Cancer Epidemiology Biomarkers & Prevention, sleep, journal, risk, Dr. Lara G. Sigurdardóttir
AACR Opposes Bill to Exempt Cigars From FDA Regulation

WASHINGTON, D.C. — The American Association for Cancer Research (AACR) formally issued letters to all members of the House of Representatives and the Senate urging them to oppose recently introduced legislation that would exempt many cigars from...

Published Wed, May 05 2013 9:00 AM by AACR News

Filed under: Press Releases, FDA, Research, Cancer, Food and Drug Administration, Media Materials, AACR, cancer prevention, lung cancer, American Association for Cancer Research, tobacco, smoking, Dr. Margaret Foti, Dr. Roy Herbst, Traditional Cigar Manufacturing and Small Business Jobs Preservation Act of 2013, S. 772, H.R. 792, cigars
Women Smokers May Have Greater Risk for Colon Cancer Than Men

Smokers of both genders had increased risk for colon cancer compared with never-smokers. The risk increase was greater for female smokers. The more and longer a woman smoked, the greater her risk. PHILADELPHIA — Smoking increased the risk for developing...

Published Tue, Apr 04 2013 1:00 PM by AACR News

Filed under: Press Releases, Research, Cancer, Media Materials, AACR, American Association for Cancer Research, tobacco, smoking, women, Cancer Epidemiology Biomarkers & Prevention, journal, risk, colon cancer, Dr. Inger Torhild Gram
Obese Men With Benign Biopsy at High Risk for Prostate Cancer

Data on obesity and prostate cancer conflict. Precancerous lesions were more common in benign biopsy specimens from obese men. After benign biopsy, obese men at higher risk for future prostate cancer. PHILADELPHIA — Obese men were more likely to...

Published Tue, Apr 04 2013 1:00 PM by AACR News

Filed under: Press Releases, Obesity, Cancer, Media Materials, AACR, cancer prevention, American Association for Cancer Research, prostate cancer, Cancer Epidemiology Biomarkers & Prevention, journal, risk, biopsy, Dr. Andrew Rundle
Water-pipe Smoking May Not Be a Safe Alternative to Cigarette Smoking

Water-pipe smoking led to exposure to agents that may cause cardiovascular diseases and leukemia. Comparison of cigarette and water-pipe smoking showed different patterns of exposure to tobacco toxicants. PHILADELPHIA — Smoking tobacco in a water...

Published Fri, Apr 04 2013 10:09 AM by AACR News

Filed under: Press Releases, Research, Cancer, Media Materials, AACR, cancer prevention, lung cancer, American Association for Cancer Research, tobacco, smoking, cigarettes, Cancer Epidemiology Biomarkers & Prevention, journal, Cardiovascular Disease, leukemia, carbon monoxide, benzene, Dr. Peyton Jacob III, hookah, water pipe
Intermittent Treatment With Vemurafenib May Prevent Lethal Drug Resistance in Melanoma

Late-stage melanomas develop resistance to vemurafenib treatment. Treatment cessation decreased tumor growth in patients with vemurafenib-resistant melanoma. An intermittent treatment regimen may help overcome drug resistance. WASHINGTON, D.C. — Vemurafenib...

Published Wed, Apr 04 2013 9:59 AM by AACR News

Filed under: Press Releases, melanoma, Media Materials, AACR, American Association for Cancer Research, 2013 Annual Meeting, Annual Meeting 2013, vemurafenib resistant tumor, Dr. Darrin Stuart, vemurafenib, BRAF mutations
More Than $5 Million in Research Grants Awarded by the Pancreatic Cancer Action Network and AACR

WASHINGTON, D.C. — The Pancreatic Cancer Action Network and the American Association for Cancer Research (AACR) awarded 14 grants totaling more than $5 million to outstanding scientists throughout the country, supporting their innovative research...

Published Wed, Apr 04 2013 9:00 AM by AACR News

Filed under: Press Releases, Research, Cancer, Media Materials, AACR, American Association for Cancer Research, pancreatic cancer, grants, funding, Pancreatic Cancer Action Network, Annual Meeting, AACR Annual Meeting 2013, 2013 Annual Meeting
AACR-Minorities in Cancer Research Honors Dr. Gabriel Hortobagyi With Jane Cooke Wright Lectureship Award

WASHINGTON, D.C. — The American Association for Cancer Research (AACR) and its Minorities in Cancer Research membership group will award Gabriel N. Hortobagyi with the Jane Cooke Wright Lectureship at the AACR Annual Meeting 2013, held in Washington...

Published Wed, Apr 04 2013 9:00 AM by AACR News

Filed under: Press Releases, Research, Cancer, Media Materials, AACR, American Association for Cancer Research, award, meeting, Annual Meeting, Minorities in Cancer Research, Jane Cooke Wright Lectureship, AACR Annual Meeting 2013, 2013 Annual Meeting, Dr. Gabriel Hortobagyi
High Calcium Intake Associated With Reduced Colorectal Adenoma Risk in Certain Individuals

Prior studies associating calcium intake and colorectal adenoma risk have been inconsistent. Variations in two specific genes were shown to modify the association. Genetic tests may help determine which patients would benefit from higher calcium intake...

Published Wed, Apr 04 2013 8:00 AM by AACR News

Filed under: Press Releases, Research, Cancer, Media Materials, AACR, American Association for Cancer Research, meeting, calcium, Annual Meeting, 2013 Annual Meeting, Dr. Xiangzhu Zhu, colorectal adenoma
RNA Interference Drug Demonstrated Activity and Safety in Phase I Trial

RNA interference drugs silence specific genes. Investigational drug silences the PLK1 gene involved in tumor growth. Most patients tolerated the drug well; some showed therapeutic benefit. WASHINGTON, D.C. — Early results from a phase I, first in...

Published Tue, Apr 04 2013 3:00 PM by AACR News

Filed under: Press Releases, Research, Treatment, Cancer, Media Materials, AACR, American Association for Cancer Research, meeting, Annual Meeting, AACR Annual Meeting 2013, 2013 Annual Meeting, phase I, RNA interference, Dr. Ramesh K. Ramanathan, RNAi
Engineered Antibody Demonstrated Safety, Efficacy in Wide Range of Advanced Tumors

The PD-L1 antibody MPDL3280A displayed antitumor activity across a range of cancer types, including lung, kidney, colon and stomach cancers. MPDL3280A was well tolerated. Phase I study results demonstrated no limiting toxicities. WASHINGTON, D.C. —...

Published Tue, Apr 04 2013 3:00 PM by AACR News

Filed under: Press Releases, Research, Cancer, Media Materials, AACR, American Association for Cancer Research, meeting, 2013 Annual Meeting, Dr. Michael S. Gordon, MPDL3280A, PD-L1, engineered antibody, death-ligand 1
Comprehensive Genomic Analysis Identified Alterations in Head and Neck Cancer That Could Lead to Targeted Therapy

Study was part of The Cancer Genome Atlas. Head and neck squamous cell carcinoma was found to be genomically heterogeneous. Many genomic alterations were shared with other squamous tumors. Data could lead to new targeted therapies. WASHINGTON, D.C. —...

Published Tue, Apr 04 2013 2:48 PM by AACR News

Filed under: Press Releases, Media Materials, AACR, American Association for Cancer Research, head and neck cancer, 2013 Annual Meeting, Annual Meeting 2013, genomic alteration, PIK3CA gene mutations, Dr. David N. Hayes, Cancer Genome Atlas, tobacco-related cancer, otolaryngology, targeted therapy

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