WASHINGTON, D.C. — The American Association for Cancer Research (AACR) formally issued letters to all members of the House of Representatives and the Senate urging them to oppose recently introduced legislation that would exempt many cigars from regulation. The Food and Drug Administration (FDA...
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Wed, May 1 2013
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Filed under: Press Releases, FDA, Research, Cancer, Food and Drug Administration, Media Materials, AACR, cancer prevention, lung cancer, American Association for Cancer Research, tobacco, smoking, Dr. Margaret Foti, Dr. Roy Herbst, Traditional Cigar Manufacturing and Small Business Jobs Preservation Act of 2013, S. 772, H.R. 792, cigars
Water-pipe smoking led to exposure to agents that may cause cardiovascular diseases and leukemia. Comparison of cigarette and water-pipe smoking showed different patterns of exposure to tobacco toxicants. PHILADELPHIA — Smoking tobacco in a water pipe resulted in a different pattern of exposure...
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Fri, Apr 19 2013
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Filed under: Press Releases, Research, Cancer, Media Materials, AACR, cancer prevention, lung cancer, American Association for Cancer Research, tobacco, smoking, cigarettes, Cancer Epidemiology Biomarkers & Prevention, journal, Cardiovascular Disease, leukemia, carbon monoxide, benzene, Dr. Peyton Jacob III, hookah, water pipe
Prevalence of benign lung disease ranged from 1.2 percent in Vermont to 25 percent in Hawaii. 2.1 percent of patients with a benign diagnosis died in the hospital after surgery. Benefits of lung cancer screening may differ widely by state. WASHINGTON, D.C. — Benign disease diagnosis rates after...
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Tue, Apr 9 2013
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Filed under: Press Releases, Research, Media Materials, AACR, lung cancer, American Association for Cancer Research, meeting, Annual Meeting, AACR Annual Meeting 2013, 2013 Annual Meeting, Dr. Stephen A. Deppen
Serum metabolites are emerging biomarkers for lung cancer detection. Bilirubin identified by metabolomic profiling had biomarker potential. Men who were smokers and had low bilirubin levels had increased risk for cancer incidence and mortality. WASHINGTON, D.C. — Smokers with low bilirubin levels were...
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Sun, Apr 7 2013
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Filed under: Press Releases, Media Materials, AACR, lung cancer, American Association for Cancer Research, Dr. Xifeng Wu, 2013 Annual Meeting, Annual Meeting 2013, smokers, lung cancer risk, incidence and mortality, bilirubin
Cisplatin-resistant non-small cell lung cancer cells expressed high levels of hyperactivated PARP1. Cells succumbed to PARP inhibitors in vitro. PARP inhibitor slowed cisplatin-resistant tumor growth in mice. PHILADELPHIA — Poly (ADP-ribose) polymerase inhibitors may be a novel treatment strategy...
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Wed, Apr 3 2013
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Filed under: Press Releases, Research, Treatment, Cancer, Media Materials, AACR, lung cancer, American Association for Cancer Research, Cancer Research, journal, non-small cell lung cancer, NSCLC, cisplatin, PARP1, PARP inhibitor, cisplatin resistance, PAR, Dr. Guido Kroemer
Ganetespib killed ALK-driven NSCLC cell lines more effectively than crizotinib. Displayed greater antitumor activity and prolonged survival in a mouse model. Potential as a new option for treating ALK-dependent lung cancers. PHILADELPHIA — A drug that indirectly impairs the function of several...
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Tue, Mar 26 2013
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Filed under: Press Releases, Research, Treatment, Cancer, Media Materials, AACR, lung cancer, American Association for Cancer Research, Cancer Discovery, journal, non-small cell lung cancer, anaplastic lymphoma kinase, ALK, NSCLC, ganetespib, resistance, crizotinib, Dr. David Proia
High levels of the inflammation marker hs-CRP associated with increased risk for cancer death. No significant association was found in women. The relationship was more common in lean participants. PHILADELPHIA — Measuring blood levels of high-sensitive C-reactive protein, an important marker of...
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Wed, Nov 7 2012
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Filed under: Press Releases, Research, inflammation, Blood test, Cancer, Media Materials, AACR, lung cancer, American Association for Cancer Research, Cancer Epidemiology Biomarkers & Prevention, journal, Dr. Minseon Park, high-sensitive C-reactive protein, hs-CRP
Melanoma, breast and prostate cancer survivors reported quality of life similar to adults without cancer. Cervical, blood, colorectal and short-survival cancer survivors reported worse health compared to adults without cancer. The researchers estimated 3.3 million American cancer survivors have poor...
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Tue, Oct 30 2012
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Filed under: Press Releases, Centers for Disease Control and Prevention, Research, Breast Cancer, melanoma, Cancer, CDC, Media Materials, AACR, lung cancer, American Association for Cancer Research, cancer survivors, prostate cancer, Cancer Epidemiology Biomarkers & Prevention, journal, National Cancer Institute, NCI, cervical cancer, quality of life, Dr. Kathryn E. Weaver, survival, blood cancer
If validated, may have the potential to produce first targeted therapy for this disease. Molecular profile of small-cell lung cancer distinct from non-small cell lung cancer. PHILADELPHIA — Newly discovered molecular differences between small-cell lung cancer and non-small cell lung cancer have...
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Thu, Sep 6 2012
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Filed under: Press Releases, Research, Treatment, Cancer, Media Materials, AACR, lung cancer, American Association for Cancer Research, Cancer Discovery, journal, PARP1, therapeutic target, Small-cell lung cancer, Dr. Lauren A. Byers, EZH2
Lack of IDO protein reduced tumor burden in primary and metastatic lung cancer models. In both models, loss of IDO improved survival. Mechanisms by which IDO promoted tumorigenesis were identified. PHILADELPHIA — Inhibitors of indoleamine 2,3-dioxygenase (IDO) are being assessed in clinical trials...
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Thu, Jul 19 2012
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Filed under: Press Releases, Research, Cancer, Media Materials, AACR, lung cancer, American Association for Cancer Research, Cancer Discovery, journal, preclinical study, IDO, IDO inhibitor, Dr. Alexander Muller